A calcium- and light-gated switch to induce gene expression in activated neurons
Despite recent advances in optogenetics, it remains challenging to manipulate gene expression in...
A Methyl-Balanced Diet Prevents CRF-Induced Prenatal Stress-Triggered Predisposition to Binge Eating-like Phenotype
Binge eating (BE) is a common aberrant form of eating behavior, characterized by overconsumption of...
CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca2+ Signals during LTP Induction, but Not Maintenance
CaMKII plays a critical role in decoding calcium (Ca2+) signals to initiate long-lasting synaptic...
Neocortical Chandelier Cells Developmentally Shape Axonal Arbors through Reorganization but Establish Subcellular Synapse Specificity without Refinement
Diverse types of cortical interneurons (INs) mediate various kinds of inhibitory control mechanisms...
Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release
Dendritic spines are the major transmitter reception compartments of glutamatergic synapses in most...
The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells
The neurotransmitter receptor subtype, number, density, and distribution relative to the location...
Movement Rate Is Encoded and Influenced by Widespread, Coherent Activity of Cerebellar Molecular Layer Interneurons
Inhibition from molecular layer interneurons (MLIs) is thought to play an important role in...
The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors
Neural circuit wiring relies on selective synapse formation whereby a presynaptic release apparatus...
LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells
Mutations in LRIT3 lead to complete congenital stationary night blindness (cCSNB). Using a cCSNB...
Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor
PaAIP2 is a genetically encoded, light-inducible inhibitor of CaMKII PaAIP2 inhibits CaMKII with...