Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain
Precise genome editing via homology-directed repair (HDR) in targeted cells, particularly in vivo...
In search of features that constitute an “enriched environment” in humans: Associations between geographical properties and brain structure
Enriched environments elicit brain plasticity in animals. In humans it is unclear which environment...
Language, mind and brain
Language serves as a cornerstone of human cognition. However, our knowledge about its neural basis...
Regional Cellular Environment Shapes Phenotypic Variations of Hippocampal and Neocortical Chandelier Cells
Different cortical regions processing distinct information, such as the hippocampus and the...
A novel region in the CaV2.1 α1 subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone
In central nervous system (CNS) synapses, action potential-evoked neurotransmitter release is...
Dynamical state transitions into addictive behavior and their early-warning signals
The theory of critical transitions in complex systems (ecosystems, climate, etc.), and especially...
Biophysics of Biochemical Signaling in Dendritic Spines: Implications in Synaptic Plasticity
Dendritic spines are mushroom-shaped postsynaptic compartments that host biochemical signal...
10-Month-Old Infants Are Sensitive to the Time Course of Perceived Actions: Eye-Tracking and EEG Evidence
Research has shown that infants are able to track a moving target efficiently – even if it is...
Using c-kit to genetically target cerebellar molecular layer interneurons in adult mice
The cerebellar system helps modulate and fine-tune motor action. Purkinje cells (PCs) provide the...
Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood
Single-nucleotide polymorphisms (SNPs) in CACNA1C, the α1C subunit of the voltage-gated L-type...