Max Planck Florida Institute for Neuroscience

Max Planck Florida Institute for Neuroscience (MPFI) researcher Dr. Alexandra Gribizis has been awarded the NIH K99/R00...

In Brief Neuroplex, a novel imaging pipeline, enables simultaneous measurements of the activity of up to nine identified...

Dr. David Fitzpatrick, Scientific Director of the Max Planck Florida Institute for Neuroscience, has been elected to the...

In brief:   How the brain tracks distance: MPFI scientists identified how hippocampal neurons encode distance traveled...

Scientists from Max Planck Florida Institute for Neuroscience in collaboration with Florida Atlantic University and East...

MPFI Scientists have discovered how two brain areas work together like an hourglass to flexibly control movement timing...

When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new study from...

PTEN Connection to Autism: Up to 25% of those with brain overgrowth and autistic spectrum disorder (ASD) carry variations...

Nerve cells that tell to us we are full also make us crave sweets Who hasn’t been there? The big meal is over...

How early visual experience builds reliable brain circuits Because it does it so well, we often take for granted how our...

New research from the Max Planck Florida Institute for Neuroscience published this week in Nature has identified a key...

Ever wish you could stop that fruit fly on your kitchen counter in its tracks? Scientists at Max Planck Florida Institute...

New research from a Max Planck Florida Institute for Neuroscience researcher could transform how we understand the way...

In a new publication, MPFI Scientists demonstrate that ALS-linked protein VAP anchors mitochondria near dendritic spines...

Max Planck Florida Institute for Neuroscience (MPFI) announces that neuroscientist Dr. Lin Tian has been appointed as its...

Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like...

New Research finds that Protein Kinase C delta activity triggered by the plasticity of just a few synapses regulates cell...

Generating adaptive behavioral responses to emotionally salient stimuli requires evaluation of complex associations...

Max Planck Florida Institute for Neuroscience (MPFI) announces that Dr. Hidehiko Inagaki has been awarded an NIH...

Brain function, much like many other areas of life, is all about balance. Excitatory neurons that increase the activity of...

Our visual perception of the world is often thought of as relatively stable. However, like all of our cognitive functions...

Nominations are now open! The Peter Gruss Young Investigator Award recognizes a young neuroscience investigator for...

Traditionally, functional representations in early visual areas are conceived as retinotopic maps preserving ego-centric...

Scientists discover a brain circuit that triggers the execution of planned movement. Planned movement is essential to our...

Everything we see, from a work of art to the laugh lines on a loved one’s face, are seen not only with our eyes but...

Researchers at the Max Planck Florida Institute for Neuroscience (MPFI) have uncovered a surprisingly complex yet...

Retinotopic maps of many visual areas are thought to follow the fundamental principles described for the primary visual...

Max Planck Florida research group leader Dr. Sarah Stern has been awarded the 2021 One Mind – Donna Friedman Rising Star...

Scientists discover a tight relationship between the local protein synthesis machinery and its nascent protein products in...

Researchers at the Max Planck Florida Institute for Neuroscience (MPFI) have developed a new imaging technique capable of...

It’s rare to get a glimpse of the life-changing research that takes place in one of the 86 world-renowned Max Planck...

The structural plasticity of dendritic spines is considered to be an important basis of synaptic plasticity, learning, and...

Max Planck Florida Institute for Neuroscience announces that Dr. Vidhya Rangaraju’s Neuroenergentics Lab has been awarded...

Identification of candidate risk genes and alteration in the expression of proteins involved in regulating inhibitory...

The activity patterns of Individual neurons are highly coordinated and synchronized within neuronal circuits in the brain...

Researchers at the Max Planck Florida Institute for Neuroscience (MPFI) have discovered that the cell adhesion protein...

The most prominent structural hallmark of the mammalian neocortical circuitry is the layer-based organization of specific...

Hidehiko Inagaki, a research group leader at the Max Planck Florida Institute for Neuroscience, has been selected as a...

The National Institute of Neurological Disorders and Stroke of the NIH has awarded Max Planck Florida’s Wang Lab an R01...

Researchers at the Max Planck Florida Institute for Neuroscience (MPFI) have uncovered a new role for a distinct...

Researchers at the Max Planck Florida Institute for Neuroscience used machine learning to develop a new, fully automated...

Max Planck Florida announces that it has formed a research collaboration partnership with Zeiss. Using an LSM 980 NLO next...

An interdisciplinary team of scientists at the Max Planck Florida Institute for Neuroscience have developed a novel...

Brain circuits are highly interconnected three-dimensional structures fabricated from components ranging vastly in size;...

Researchers from the Max Planck Florida Institute for Neuroscience Uncover a Surprising New Role for the Protein Centaurin...

The first of its kind in uniting Universities and Max Planck Institutions on both sides of the Atlantic, the International...

Each year, a committee of neuroscientists from the Society of the Neuroscience convene to evaluate applications for The...

The first of its kind in uniting Universities and Max Planck Institutions on both sides of the Atlantic, the International...

Neurexins are a family of presynaptic cell adhesion proteins that regulate synaptic structure and maintain normal synaptic...

Integrin receptors regulate normal cell function processes such as signaling, cell migration, adhesion to the...

Amygdala plays crucial roles in emotional learning. The lateral amygdala (LA) is the input station of the amygdala, where...

Dr. Vidhya Rangaraju was recently recruited by the Max Planck Florida Institute for Neuroscience (MPFI) to investigate the...

The $300,000 award supports exceptional young faculty who demonstrate innovation in research. Dr. Inagaki is one of only...

Researchers at the Max Planck Florida Institute for Neuroscience identify three distinct cortical representations that...

Dr. Yasuda received a perfect score on his application, a rare accomplishment among even the most experienced scientists...

Researchers at the Max Planck Florida Institute for Neuroscience have developed a first-of-its-kind approach for studying...

Scientists from Max Planck Florida Institute for Neuroscience (MPFI) and the University of Iowa Carver College of Medicine...

MPFI announces that Dr. Hidehiko Inagaki has joined the institute as a research group leader studying Neural Dynamics and...

This is an intensive and comprehensive laboratory-oriented course focusing on applying imaging techniques to neuroscience...

The calyx of Held, a large glutamatergic presynaptic terminal in the auditory brainstem undergoes developmental changes to...

Dr. Ilaria Drago, Head of Education Outreach for the Max Planck Florida Institute for Neuroscience, was named the Rising...

Understanding how cortical inhibition shapes circuit function requires identifying the connectivity rules relating the...

Researchers at the Max Planck Florida Institute for Neuroscience uncovered a diverse palette of inhibition within layer...

Could AI be used to help rid the ocean of trash? Can machine learning prevent thousands of unnecessary deaths from...

Neurotransmissions, a podcast produced by the Max Planck Florida Institute for Neuroscience is growing and is now...

CRISPR/Cas-based technologies have revolutionized genetic approaches to addressing a wide range of neurobiological...

The power and convenience of modern-day word-processing programs, like Microsoft Word, have revolutionized our daily tasks...

  The Max Planck Florida Institute for Neuroscience (MPFI) will receive $1,639,101 as part of the recently signed...

CaMKIIα plays an essential role in decoding Ca²⁺ signaling in spines by acting as a leaky Ca²⁺ integrator with the time...

In an increasingly connected world, translators and interpreters play a key role in the exchange of ideas and information...

The Max Planck Florida Institute for Neuroscience (MPFI) held its 8th annual Brain Bee Challenge Saturday April 6, 2019...

The brain must make sense of external stimuli to generate relevant behavior. We used a combination of in vivo approaches...

Researchers at Max Planck Florida Institute for Neuroscience have revealed a special input pathway that holds the key to...

The Max Planck Florida Institute for Neuroscience announces the appointment of two Max Planck Society Fellows, Drs...

Dr. Ryohei Yasuda of the Max Planck Florida Institute for Neuroscience (MPFI) has received a grant by the National...

Researchers at the Max Planck Florida Institute for Neuroscience have developed a new combination of technologies that...

Callosal projections are thought to play a critical role in coordinating neural activity between the cerebral hemispheres...

Functionally and anatomically distinct cortical substructures, such as areas or layers, contain different principal neuron...

Researchers at Max Planck Florida Institute for Neuroscience have developed a novel technique capable of tracing intricate...

The mammalian cerebral cortex is divided into different areas according to their function and pattern of connections...

The Max Planck Florida Institute for Neuroscience (MPFI) announces a new “labs@location” partnership agreement between the...

The Max Planck Florida Institute for Neuroscience and the Phillip and Patricia Frost Museum of Science in Downtown Miami’s...

The FAU Max Planck Academy will Serve as a Pioneer Model in STEM Education The brightest STEM high school students can now...

The Max Planck Florida Institute for Neuroscience (MPFI) announces that Dr. Gloria Choi is the second biennial Peter Gruss...

The principles governing the functional organization and development of long-range network interactions in the neocortex...

One of the outstanding mysteries of the cerebral cortex is how individual neurons develop the proper synaptic connections...

The concept of “finding your happy place” just got a big boost thanks to a Max Planck Florida neuroscientist and the NIH...

The Max Planck Florida Institute for Neuroscience (MPFI) hosted 70 local high school students and their teachers for...

The Max Planck Florida Institute for Neuroscience (MPFI) announces that Dr. Jason Christie, MPFI Research Group Leader...

Motor learning involves neural circuit modifications in the cerebellar cortex, likely through re-weighting of parallel...

Researchers at the Max Planck Florida Institute for Neuroscience (MPFI) have discovered a new role for inhibition...

Purkinje cell dendrites convert excitatory climbing fiber input into signals that instruct plasticity and motor learning...

Researchers at the Max Planck Florida Institute for Neuroscience discover a fundamentally new role for inhibition in the...

To encode specific sensory inputs, cortical neurons must generate selective responses for distinct stimulus features. In...

Read More Here Original Publication

Researchers at the Max Planck Florida Institute for Neuroscience show that protein Kinase C is a novel information...

The protein kinase C (PKC) enzymes have long been established as critical for synaptic plasticity. However, it is unknown...

Synaptic plasticity, the cellular basis for learning and memory, is mediated by a complex biochemical network of signaling...

Researchers at the Max Planck Florida Institute for Neuroscience release open source software, connecting and building the...

 Read More Here Original Publication

Researchers at the Max Planck Florida Institute for Neuroscience discovered a new way that the protein RGS14 functions as...

Pyramidal neurons in hippocampal area CA2 are distinct from neighboring CA1 in that they resist synaptic long-term...

Florida Atlantic University President John Kelly, Max Planck Society President Martin Stratmann, and David Fitzpatrick...

Read More Here Original Publication

Researchers at the Max Planck Florida Institute for Neuroscience discovered local order of dendritic spine functional...

Substantial evidence at the subcellular level indicates that the spatial arrangement of synaptic inputs onto dendrites...

 Read More Here Original Publication

Scientists develop a new tool for precise genome editing in neurons Genome editing technologies have revolutionized...

Precise genome editing via homology-directed repair (HDR) in targeted cells, particularly in vivo, provides an invaluable...

Researchers at the Max Planck Florida Institute for Neuroscience show that location matters when it comes to brain cells’...

Work will use state of the art imaging techniques to provide new insights critical for addressing numerous visual...

Different cortical regions processing distinct information, such as the hippocampus and the neocortex, share common...

A new study conducted by researchers at the Max Planck Florida Institute for Neuroscience uncovers critical aspects of...

Ryohei Yasuda, Ph.D., Max Planck Florida Institute for Neuroscience’s (MPFI) Scientific Director, was one of two...

In central nervous system (CNS) synapses, action potential-evoked neurotransmitter release is principally mediated by CaV2...

Dendritic spines are mushroom-shaped postsynaptic compartments that host biochemical signal cascades important for...

The cerebellar system helps modulate and fine-tune motor action. Purkinje cells (PCs) provide the sole output of the...

Researchers at the Max Planck Florida Institute for Neuroscience (MPFI) are working to understand how different types of...

Despite recent advances in optogenetics, it remains challenging to manipulate gene expression in specific populations of...

Read more here. Original Publication: Lee, D., Hyun, J.H., Jung, K., Hannan, P., and Kwon, H.-B. (2017). A calcium- and...

Researchers at Max Planck Florida Institute for Neuroscience develop a technique to visualize and control the neural...

While it is generally appreciated that learning involves the structural rearrangement of neuronal circuits, the underlying...

Researchers at the Max Planck Florida Institute for Neuroscience identify the wiring process of a unique type of...

Read more here Original Publication: Chang, J.-Y., Parra-Bueno, P., Laviv, T., Szatmari, E.M., Lee, S.-J.R., and Yasuda, R...

CaMKII plays a critical role in decoding calcium (Ca2+) signals to initiate long-lasting synaptic plasticity. However, the...

Researchers at Max Planck Florida Institute for Neuroscience optimize imaging methods to visualize CaMKII activation...

Researchers at the Max Planck Florida Institute for Neuroscience discovered that interneurons within the molecular layer...

Diverse types of cortical interneurons (INs) mediate various kinds of inhibitory control mechanisms to balance and shape...

Neuroscientists in Göttingen debunk key tenet of brain development According to the current thinking in neuroscience...

The neurotransmitter receptor subtype, number, density, and distribution relative to the location of transmitter release...

Inhibition from molecular layer interneurons (MLIs) is thought to play an important role in cerebellar function by...

Researchers develop a light-sensitive technique to visualize and manipulate neuromodulation with unprecedented spatial and...

Researchers develop a light-sensitive technique to visualize and manipulate neuromodulation with unprecedented spatial and...

Neural circuit wiring relies on selective synapse formation whereby a presynaptic release apparatus is matched with its...

Mutations in LRIT3 lead to complete congenital stationary night blindness (cCSNB). Using a cCSNB mouse model lacking Lrit3...

Learn more here: Scientists develop light-controllable tool to study CaMKII kinetics in learning and memory Original...

Researchers at Max Planck Florida Institute for Neuroscience have developed a photo-inducible CaMKII inhibitor to study...

PaAIP2 is a genetically encoded, light-inducible inhibitor of CaMKII PaAIP2 inhibits CaMKII with high specificity and with...

Highly sensitive ERK and PKA FLIM sensors with novel fluorophore pair Image ERK and PKA activation in single dendritic...

Highlights Highly sensitive ERK and PKA FLIM sensors with novel fluorophore pair Image ERK and PKA activation in single...

Researchers from Max Planck Florida Institute for Neuroscience designed new sensors to study the activity of signaling...

Inhibitory neurons respond selectively to stimulus orientation in ferret visual cortex Inhibitory tuning cannot be...

Researchers at the Max Planck Florida Institute for Neuroscience unravel the functional organization of inhibitory neurons...

Neurons and neural networks often extend hundreds of micrometers in three dimensions. Capturing the calcium transients...

Scientists at Max Planck Florida Institute for Neuroscience are working to understand how neurons in the cerebellum, a...

Somatic depolarization spreads strongly into stellate cell axons Depolarization results in ultra-rapid AP broadening and...

Few tools exist to visualize and manipulate neurons that are targets of neuromodulators. We present iTango, a light- and...

Max Planck Florida Institute for Neuroscience’s Popular Research Conference Attracted Its Largest Audience Yet Twenty of...

Advanced super-resolution imaging technology benefiting life sciences will now be available in the U.S. The Max Planck...

Excluding the ribosome and riboswitches, developing small molecules that selectively target RNA is a longstanding problem...

Scheduled for Feb 13, 2017 Thomas Südhof of Stanford University School of Medicine presents a plenary lecture at Max...

This presentation was live streamed on February 14th, 2:45-3:45PM EST. It will not be available after that time. Scheduled...

Researchers at Max Planck Florida Institute for Neuroscience have developed new software to study synaptic plasticity in...

Long-term structural plasticity of dendritic spines plays a key role in synaptic plasticity, the cellular basis for...

Streamed live from Max Planck Florida Institute for Neuroscience on Jan 18, 2017 Spatial functions of the hippocampus and...

Syt2 is the Ca2+ sensor of fast transmitter release at a cerebellar GABAergic synapse Syt2 triggers transmitter release...

The Max Planck Florida Institute for Neuroscience’s Sunposium™ conference brings hundreds of the world’s most...

A fundamental impediment to understanding the brain is the availability of inexpensive and robust methods for targeting...

We describe a red-shifted fluorescence resonance energy transfer (FRET) pair optimized for dual-color fluorescence...

Researchers at Max Planck Florida Institute for Neuroscience and Stanford University teamed up to develop a new molecular...

Work will focus on developing new optogenetic technologies to understand learning and memory functions A $1.4 million...

Max Planck Florida Institute for Neuroscience Honors Collaboration, Creativity and Curiosity-Driven Research The Max...

Course Description This is an intensive and comprehensive laboratory-oriented course focusing on applying imaging...

Researchers from Max Planck Florida Institute for Neuroscience, Duke University, and collaborators have identified a novel...

Learn more here Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity Nathan G...

Learn more here Autocrine BDNF-TrkB signalling within a single dendritic spine Stephen C. Harward*, Nathan G. Hedrick*...

Brain-derived neurotrophic factor (BDNF) and its receptor TrkB are crucial for many forms of neuronal plasticity...

The Rho GTPase proteins Rac1, RhoA and Cdc42 have a central role in regulating the actin cytoskeleton in dendritic spines...

Dendrites of cortical pyramidal neurons contain intermingled excitatory and inhibitory synapses. We studied the local...

Astrocytes form an intricate partnership with neural circuits to influence numerous cellular and synaptic processes. One...

De novo synaptogenesis induced by GABA in the developing mouse cortex Won Chan Oh, Stefano Lutzu, Pablo E Castillo, and...

Researchers at the Max Planck Florida Institute for Neuroscience are optimizing optogenetic methods for circuit mapping...

The Electron Microscopy Core from Max Planck Florida Institute for Neuroscience will host an exciting 2-day workshop...

We describe refinements in optogenetic methods for circuit mapping that enable measurements of functional synaptic...

Abstract Neuroscience research has been revolutionized by the use of recombinant viral vector technology from the basic...

Abstract Two-photon (2P) imaging has proven to be a powerful tool for investigating neural structure and function both in...

Two-photon (2P) imaging has proven to be a powerful tool for investigating neural structure and function both in brain...

Neuroscience research has been revolutionized by the use of recombinant viral vector technology from the basic...

De novo synaptogenesis induced by GABA in the developing mouse cortex Won Chan Oh, Stefano Lutzu, Pablo E Castillo, and...

Researchers from Max Planck Florida Institute for Neuroscience optimized a spatiotemporally controlled method that induces...

Work will focus on calcium signaling properties of astrocytes in the visual cortex Dr. James Schummers, Research Group...

Lesley Colgan, Ph.D. is a Postdoctoral Researcher in the lab of Scientific Director Ryohei Yasuda, Ph.D. Her research...

Researchers at the Max Planck Florida Institute for Neuroscience uncover important organizational features of axonal...

Orientation selectivity and the functional clustering of synaptic inputs in primary visual cortex Daniel E Wilson, David E...

Study by Max Planck Florida scientists points to an active role for dendrites in cortical processing – Dendrites are...

The majority of neurons in primary visual cortex are tuned for stimulus orientation, but the factors that account for the...

Orange-red fluorescent proteins (FPs) are widely used in biomedical research for multiplexed epifluorescence microscopy...

Joseph Schumacher, Ph.D., a Postdoctoral Researcher in the Fitzpatrick Lab at Max Planck Florida Institute for...

Learn more here.

Researchers at the Max Planck Florida Institute for Neuroscience have created a new scalable, efficient and cost-effective...

Circuits in the visual cortex integrate the information derived from separate ON (light-responsive) and OFF (dark...

Older concepts of a hard-wired adult brain have been overturned in recent years by in vivo imaging studies revealing...

Topology of ON and OFF inputs in visual cortex enables an invariant columnar architecture Kuo-Sheng Lee, Xiaoying Huang...

Neurons in our brain do a remarkable job of translating sensory information into reliable representations of our world...

Award Recognizes MPFI’s Commitment to Helping Students Succeed, Industry Grow Miami, FL – The Max Planck Florida Institute...

A scalable and high-throughput method to identify precise subcellular localization of endogenous proteins is essential for...

Cortical inhibition is mediated by diverse inhibitory neuron types that can each play distinct roles in information...

Researchers at the Max Planck Florida Institute for Neuroscience focus on visualizing and manipulating neuronal activity...

“There was a very popular saying in China when I was in high school: The 21st century is the century of biology,” said Ye...

During cortical circuit development in the mammalian brain, groups of excitatory neurons that receive similar sensory...

A recent study shows conclusively that the koniocellular layers of the marmoset dorsal lateral geniculate nucleus have...

Optimization of imaging and behavior approaches provides unprecedented insight into organizational principles of motor...

Purkinje cells (PCs) are a major site of information integration and plasticity in the cerebellum, a brain region involved...

Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse Mónica S...

Researchers at the Max Planck Florida Institute for Neuroscience have uncovered a critical molecule that regulates...

While some things may be ‘as simple as black and white’, this has not been the case for the circuits in the brain that...

Modular Representation of Luminance Polarity in the Superficial Layers of Primary Visual Cortex Gordon B. Smith1, David E...

Dr. David Auth, renowned scientist and MPFI Board Member, and wife Nancy inspired by institute’s progress in pioneering...

Award recognizes significant contributions to the scientific community through collaboration, creativity, and curiosity...

Award Recognizes Yasuda’s Creativity and Innovation in Biomedical Research Max Planck Florida Institute for Neuroscience...

The Max Planck Florida Institute for Neuroscience (MPFI), along with the Frankfurt Institute for Advanced Studies (FIAS)...

In order to understand memory deficit and neuronal loss in mouse models of Alzheimer’s disease, the Bright Focus...

The Federation of American Societies for Experimental Biology (FASEB) has honored Samuel M. Young, Jr. Ph.D., a Max Planck...

Work will focus on visualizing and manipulating neuronal activity in individual neurons Dr. Hyungbae Kwon, Research Group...

Nobel Prize Laureate Among an Impressive Array of Speakers at Max Planck Florida Institute for Neuroscience’s Widely...

Learn more about Sunposium

Work will focus on a newly discovered circuit in the visual cortex Dr. David Fitzpatrick, Scientific Director and CEO at...

Researchers at the Max Planck Florida Institute for Neuroscience and Kanazawa University (Japan) have succeeded in imaging...

Research aims to reveal new cellular and molecular mechanisms involved in the early stages of hearing Samuel Young, Jr...

Researchers at the Max Planck Florida Institute for Neuroscience and the Pasteur Institute have uncovered a key factor in...

Researchers report substantial postnatal changes in the functional properties of brain circuits that enhance their ability...