Philipp Brand receives an ERC Starting Grant Microbial symbionts are widespread across the animal kingdom and can...
Research News
Neural Circuits, Microbes, and Behavioral Evolution
Research That Inspires
Three Weeks of Science, New Perspectives and Discoveries for the Max Planck Junior Scholars 2026 How is scientific...
Erin Schuman receives Kavli Prize
The director of the Max Planck Institute for Brain Research is among the winners of the internationally renowned Kavli...
Ribosomes in Pairs: A Survival Strategy Inside Stressed Cells
Scientists discover RNA-driven mechanism that helps neurons endure prolonged starvation Ribosomes, the cell’s protein...
Two New Research Groups join the Max Planck Institute for Brain Research
In 2025, the Max Planck Institute for Brain Research welcomes two new Research Group Leaders: Dr. Philipp Brand and Dr...
Erin Schuman elected as a Member of the National Academy of Medicine
The neuroscientist is honored for her pioneering research revealing how local protein production shapes synaptic...
A Molecular Atlas of the Hippocampus: Mapping RNAs and Proteins at Synaptic Resolution
New integrative study uncovers the spatial organization of transcripts and proteins in the mouse hippocampus, offering...
Ribosomes On the Road: Neurons Assemble Protein Factories Far from the Nucleus
New study shows ribosome biogenesis can occur within neuronal branches, challenging traditional textbook biology...
Gilles Laurent is awarded the Louis-Jeantet Prize for Medicine in 2025
Gilles Laurent is awarded the 2025 Louis-Jeantet Prize for Medicine for his pioneering work on the operations of neurons...
Neural circuits for survival instincts
Vanessa Stempel receives an ERC Starting Grant to investigate brain circuits supporting instinctive behaviors ...
Erin Schuman awarded prestigious Körber Prize for pioneering research on neuronal protein synthesis
Erin Schuman, director at the Max Planck Institute for Brain Research in Frankfurt, has been awarded the prestigious...
Gilles Laurent awarded prestigious ERC Advanced Grant for research on cephalopod camouflage
Cephalopod camouflage is one of the most fascinating behaviors in the animal kingdom and is of great importance to...
New study reveals ‘moonlighting’ function of part of the brain’s protein destruction machine at synapses
A major component of the cell’s protein destruction machine moonlights at brain synapses A new study by researchers at the...
Erin Schuman elected to American Academy of Arts and Sciences
Max Planck Institute for Brain Research director and Brain Prize winner Erin Schuman has been elected to the American...
Erin Schuman is awarded the Brain Prize 2023
Max Planck scientist receives the most prestigious research prize in neuroscience together with two other researchers Erin...
Competition between brain hemispheres during sleep
Human beings are bilaterally symmetrical. As such, our brains are made of two halves called hemispheres, that communicate...
Modeling the turtle brain provides insights: Routing activity in the visual cortex
New study uses computer simulations to explore how patterns of spikes propagate in neuronal networks constrained by the...
In the zone for memories
Scientists discover that the mysterious ‘zone of uncertainty’ enables the brain to rapidly form new memories The neocortex...
A molecular atlas of an Australian dragon’s brain sheds new light on over 300 million years of brain evolution
These days, dragons are keeping Game of Thrones fans on their toes. But they are also providing important insights into...
Different flavors of inhibition save the day
Scientists gain insights on how deprivation-induced synaptic changes affect excitatory and inhibitory firing rates in the...
Silence for thought: special interneuron networks in the human brain
Scientists map prominent differences in the neural circuits of mice, monkeys, and human The analysis of the human brain is...
Never Forget
A memorial sculpture at the Max Planck Institute for Brain Research commemorates the tragic history of the predecessor...
Prof. Julijana Gjorgjieva is awarded the Heinz Maier-Leibnitz Prize
DFG and BMBF award the neuroscientist with the most important prize for early career researchers in Germany Our...
Erin Schuman wins the FEBS | EMBO Women in Science Award 2022
The neuroscientist is honoured for her exceptional achievements in the life sciences and for being an inspiring role model...
Two new research groups at the Max Planck Institute for Brain Research
Alison Barker and Vanessa Stempel joined the Max Planck Institute for Brain Research as new research group leaders in 2021...
Learning to see better
The flash of an image on the retina sends millions of neurons to work. ESI scientists show that their responses become...
The goal in mind
Scientists discover the brain’s internal goal map enabling animals to navigate precisely to a chosen destination. Animals...
Old dog learns a new trick
Neuronal ribosomes dynamically change their composition in a context-dependent manner. Ribosomes are large, multi-protein...
Brain cells work remotely
Neurons use local protein synthesis as dominant source of protein production. To form and modify synaptic connections and...
Local supply chains in neurons: who gets the goods?
Scientists discover a tight relationship between the local protein synthesis machinery and its nascent protein products in...
A molecular switch to adjust synapses
Neurons phosphorylate their proteins in order to sense and respond to changes in network activity Homeostatic scaling is a...
Hertie-Foundation and FENS award Eric Kandel Young Neuroscientists Prize to Julijana Gjorgjieva
Max Planck scientist is recognized for outstanding achievements in the field of computational and theoretical neuroscience...
Wiring up neural circuits at subcellular precision
Researchers unravel a mechanism behind distinct organizational features in the visual cortex of mouse and ferrets Recent...
Wiring diagrams can shed light on how brains operate
A novel approach to connectomics gives insights on the validity of brain models Our brains house about 85 billion neurons...
Hot on the messenger’s trail
Scientists track mRNA molecules and newly synthesized proteins within living neurons Neurons communicate across vast...
How the brain teaches itself to see
A computational model gives insights into how spontaneous neural activity shapes connectivity in the developing visual...
Charting the developing brain
Researchers use connectomic mapping in the developing cortex to uncover the developmental wiring rules for inhibitory...
What social distancing does to a brain
Scientists discover a neuropeptide that reflects the current state of a fish’s social environment. Have you recently...
Proteins in motion
Membrane proteins are more efficient at reaching distal dendrites than soluble proteins. Proteins are the essential...
From the inside out – how the brain forms sensory memories
New study identifies a region of the thalamus as a key source of signals encoding past experiences in the neocortex. The...
Virtual Seminar Series
The Max Planck Institute for Brain Research is presenting a series of virtual seminars in 2021 by excellent postdoctoral...
Using walls to navigate the room
Scientists discover a brain circuit that signals the direction and distance of boundaries in the environment to help...
Tuning in on cortical circuit dynamics
Neurons use homeostatic mechanisms to maintain stability despite experience-dependent network alterations. Neural circuits...
Neural networks in the spotlight
Scientists develop a computational model to predict and interpret the outcome of optogenetic experiments. Optogenetic...
Tatjana Tchumatchenko has been awarded an ERC Starting Grant
Tatjana Tchumatchenko, Research Group Leader at the Max Planck Institute for Brain Research, has received this prestigious...
ALBA-FKNE Diversity Prize 2020 awarded to Erin Schuman
Professor Erin Schuman has been awarded the Diversity prize 2020 for her contribution to advancing gender equality in...
Dissecting the architecture of the brain
Scientists immerse themselves into the structure of networks Under the framework of a new Marie Skłodowska Curie...
Hidden away: An enigmatic mammalian brain area revealed in reptiles
Scientists find, in reptiles, a brain area previously suspected to play a role in mammalian higher cognitive processes...
Keeping the balance: An unexpected new role for an enzyme regulating neuronal proteostasis
Scientists find how inhibition of the protein machine which degrade unneeded or damaged proteins leads to a compensatory...
Erin Schuman is elected member of the United States National Academy of Sciences
The National Academy of Sciences is recognizing Erin Schuman for her outstanding contributions to neuronal cell biology...
Stability despite perturbation – a tale of neural circuits
Scientists gain insights into properties that enable neural circuit stability after specific perturbations. A neural...
Solitary ribosomes supply synapses with protein
Scientists reveal surprising insights into protein synthesis in neurons. The complex architecture of brain cells requires...
Erin Schuman is awarded the 2020 Louis-Jeantet Prize for Medicine
The Louis-Jeantet Foundation is recognizing Erin Schuman for her work on local protein synthesis at neuronal synapses. The...
The neocortex is critical for learning and memory is more important than expected
New study finds that the auditory cortex is indispensable for threat memory, in particular for naturalistic stimuli. A...
Deep inside the brain: Unraveling the dense networks in the cerebral cortex
Researchers use 3-dimensional electron microscopy to map the local connectome in the cerebral cortex. Mammalian brains...
Cascading activity in a cortical network
New study provides unprecedented insights on the nature of neural processing in the cortex. Brain computation is carried...
Location matters: The production site predicts protein abundance
Scientists develop a mathematical model to predict the density and dynamics of proteins in the brain Proteins are the...
Proteins are needed for memory, but where and when?
A genetically encodable cell-type-specific protein synthesis inhibitor Long-lasting memories in the brain are made...
Protein supply in long nerves: how do neurons do it?
Proteins, the essential building blocks and machines of all cells, have a limited lifetime. Within the span of a week or...
Human Frontier Science Program (HFSP) has recently awarded a prestigious, three-year, cross-disciplinary fellowship to postdoc Chao Sun to support his research.
Chao Sun started his research in the Schuman Lab in August 2018 and investigates the “sociology” of neuronal...
Gilles Laurent receives second ERC Advanced Grant for project on sleep evolution
With this prestigious grant of about 2.5 million Euro, Gilles Laurent, Director at the Max Planck Institute for Brain...
Humboldt Research Fellowships for Anna Schroeder (Letzkus Lab) and Chao Sun (Schuman Lab)
The Alexander von Humboldt Foundation has recently awarded prestigious fellowships to both postdocs at the Max Planck...
Local translation in neuronal processes
Neurons exhibit a unique degree of spatial compartmentalization and are able to maintain and remodel their proteomes...
Marie Curie Fellowship for postdoc Anna Schroeder (Letzkus Lab)
The European Commission has recently awarded Anna a Marie Sklodowska-Curie Individual Fellowship to work abroad. Anna...
New call for the Max Planck Junior Scholars Program now open
High-school students (10th and 11th graders) can apply till February 15, 2019 The Max Planck Junior Scholars Program...
Cell-type-specific metabolic labeling, detectionand identification of nascent proteomes in vivo
A big challenge in proteomics is the identification of cell-type-specific proteomes in vivo. This protocol describes how...
Spatially restricted mitochondria fuel the extensive local protein synthesis needed to support synaptic plasticity
Local translation meets protein turnover and plasticity demands at synapses, however, the location of its energy supply is...
What fuels memory?
Mitochondria are essential for local protein synthesis and synaptic plasticity in neurons In order to respond both swiftly...
Two EMBO Long-term Fellowships for Postdocs from the MPI for Brain Research
Both Anna Schröder and Chao Sun have been awarded a prestigious two-year grant to support post-doctoral research in a...
Julijana Gjorgjieva has been awarded the 2018 Research Prize from Peter and Traudl Engelhorn Foundation
Julijana Gjorgjieva is one of the four Max Planck Research Group Leaders at the Institute and received the Research Prize...
Maria Antonietta Tosches Selected as Next Generation Leader for the Allen Institute for Brain Science
Max Planck Institute for Brain Research researcher Maria Antonietta Tosches has been nominated from a pool of...
Erin Schuman has been awarded the Mika Salpeter Lifetime Achievement Award
The Society for Neuroscience (SfN) recognizes Erin Schuman for her outstanding career achievements in neuroscience and for...
Elucidating the control and development of skin patterning in cuttlefish.
Few animals provide a readout that is as objective of their perceptual state as camouflaging cephalopods. Their skin...
Master of the tree – novel form of dendritic inhibition discovered
A unique feature that sets neurons apart from all other cells are their beautiful, highly elaborate dendritic trees. These...
Laura Bernáez Timón (Tchumatchenko Lab) has been awarded a Fellowship from the Joachim Herz Foundation
Add-on Fellowship for Interdisciplinary Life Science offers funding for two years. Laura Bernáez Timón is a graduate...
Raunak Basu – Ito Lab – has received funding from the Alexander von Humboldt Foundation
The Humboldt Research Fellowship for Postdoctoral Researchers will support Raunak for a period of 24 months as of March...
The art of the brain
New exhibition at the Max Planck Institute for Brain Research On the Max Planck Day (September 14), the Max Planck...
2018 Bar of Science event very successful
As a prelude to the Max Planck Day, MPI-BR scientists brought their exciting research to local bars. On September 13...
Competition for synaptic building blocks shapes synaptic plasticity
Changes in the efficacies of synapses are thought to be the neurobiological basis of learning and memory. The efficacy of...
Korbinian Brodmann returns to Frankfurt and MPI-BR
On September 14, the Max Planck Institute for Brain Research opened an exhibition about life and work of the...
Blood vessels instruct brain development
Neurovascular communication in the brain Function and homeostasis of the brain relies on communication between the complex...
FluoEM, virtual labeling of axons in 3-dimensional electron microscopy data for long-range connectomics
The labeling and identification of long-range axonal inputs from multiple sources within densely reconstructed EM datasets...
How we decide on where to go
Neuroscientists discover a mechanism for brain-wide communication when selecting a route towards a destination. Route...
Julijana Gjorgjieva has been awarded an ERC Starting Grant
Research Group Leader Julijana Gjorgjieva at the Max Planck Institute for Brain Research has received this prestigious...
Cell type and environment influence protein turnover in the brain
New findings provide insight on how the components of different cells in the brain are altered, which could affect our...
Marina Elaine Wosniack (postdoc at the Gjorgjieva Lab) receives a Capes-Humboldt Research Fellowship
This two-year grant will support her research project on the neural circuits underlying Drosophila (fruit fly) larvae...
Tracing cerebral cortex evolution, cell by cell
Molecular atlases of turtle and lizard brains shed light on the evolution of our own brain. Our cerebral cortex, a sheet...
Alternative 3′ UTRs Modify the Localization, Regulatory Potential, Stability, and Plasticity of mRNAs in Neuronal Compartments
Neurons localize mRNAs near synapses where their translation can be regulated by synaptic demand and activity. Differences...
Of men and mice
Max Planck Researchers identify rapid neuromodulation of interneurons in human neocortex. The human neocortex mediates...
Non-coding RNA reveals its secrets
Scientists from the Schuman Lab at the Max Planck Institute for Brain Research have investigated the variety of structures...
Max Planck neuroscientist Hiroshi Ito is awarded a prestigious grant from the Human Frontiers Science Program
Research Group Leader Hiroshi Ito (Max Planck Institute for Brain Research, Frankfurt, Germany) has been awarded a Young...
Neural networks: All versatility in one model
Max Planck researchers Nataliya Kraynyukova and Tatjana Tchumatchenko have explored how the structure of neural networks...
Stabilized supralinear network can give rise to bistable, oscillatory, and persistent activity
A hallmark of cortical circuits is their versatility. They can perform multiple fundamental computations such as...
Grant by Christiane Nüsslein Volhard Foundation for Anja Gemmer extended
Anja Gemmer works in the Schuman Lab where she studies the role of oxytocin in zebrafish. Anja is delighted about the...
Tatjana Tchumatchenko is awarded a DFG grant to investigate contrast invariance.
Tatjana’s project is part of the Priority Programme “Computational Connectomics”, a newly established research programme...
Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses
In homeostatic scaling at central synapses, the depth and breadth of cellular mechanisms that detect the offset from the...
New proteins for new memories
Researchers at the Max Planck Institute for Brain Research have found a way to measure newly synthesized proteins in...
Spatial Information in a Non-retinotopic Visual Cortex
Turtle dorsal cortex (dCx), a three-layered corticalarea of the reptilian telencephalon, receives inputsfrom the retina...
How turtles analyze their visual environment
In mammals, such as cats or humans, the six-layered cerebral cortex is one of the most important brain areas for conscious...
Tatjana Tchumatchenko recognized as one of the 25 young innovators
As part of its 25th anniversary, Focus Magazine selected Tatjana Tchumatchenko (Max Planck Research Group Leader at our...
Andreas Nold receives Add-on Fellowship for Interdisciplinary Science from the Joachim Herz Stiftung
In the Tchumatchenko Lab, Andreas models the interactions between different types of cells in the brain causing multiple...
Julijana Gjorgjieva receives 2017 NARSAD Young Investigator Award to study spontaneous activity in the developing mouse brain
With the grant from the Brain and Behavior Research Foundation, Max Planck Research Group Leader Julijana Gjorgjieva will...
Anne Biever receives prestigious grant from Alexander von Humboldt Foundation
Postdoc Anne Biever was recently awarded a Humboldt Research Fellowship for Postdoctoral Researchers. These fellowships...
Tatjana Tchumatchenko receives MainCampus Educator Award
Tatjana Tchumatchenko, the leader of Theory of Neural Dynamics Group at the Max Planck Institute for Brain Research, has...
Detecting new proteins in behaving mice
By using innovative labeling methods, Max Planck researchers develop a technique to measure newly synthesized proteins in...
Applications and limitations of linear response functions in models of neural circuits.
All functions of the brain are generated by neural circuits with complex nonlinear interactions and feedback loops. In the...
Traudl Engelhorn Foundation Postdoctoral Fellowship for Paul Donlin-Asp
Paul Donlin-Asp, postdoctoral fellow in the Schuman lab, was awarded a Peter and Traudl Engelhorn Foundation Postdoctoral...
Highly precise wiring in the Cerebral Cortex
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is...
10-fold speed up for the reconstruction of neuronal networks
Flying through the brain thanks to a novel in-browser tool Scientists working in “connectomics,” a research...
Erin Schuman elected as member of Leopoldina
We are happy to announce that Erin Schuman, Director at the Max Planck Institute (MPI) for Brain Research, was recently...
Wolf Singer elected to National Academy of Sciences
Wolf Singer, Director Emeritus at the Max Planck Institute for Brain Research, is one of the 21 foreign associates...
Hiroshi Ito receives prestigious prize from Japan Neuroscience Society
Hiroshi Ito has been awarded the Young Investigator Award of the Japan Neuroscience Society for his investigation of...
Cell number determines structure of neural maps
Frankfurt researchers find a simple explanation for the typical patterns of nerve cells inside neural maps The human brain...
Erin Schuman receives her second ERC Advanced Grant for NeuroRibo project
With this prestigious grant of 2.5 million Euro, Erin Schuman, Director at the Frankfurt-based Max Planck Institute for...
Hiroshi Ito, Research Group Leader at the Max Planck Institute for Brain Research, receives an ERC Starting Grant to investigate neural circuits for goal-directed spatial navigation
Last year, Hiroshi moved from the Lab of Nobel laureates May-Britt and Edvard Moser in Trondheim, Norway to the MPI in...
How much information can we get from a spike?
Neurons communicate via spikes but how they use those short pulses to code information is still an open question. Recent...
Bright Spots in Brain Cells
Witnessing the birth of a tiny RNA at brain synapses Proteins are the building blocks of all cells. They are made from...
Sweetening neurotransmitter receptors and other neuronal proteins
Researchers discover a “sugar-code” for neuronal membrane proteins. To rapidly carry information throughout the body...
Seeking balanced networks: how neurons adjust their proteins during homeostatic scaling
Neurons adjust their synapses by altering the synthesis of hundreds of proteins to regulate synaptic strength and network...
Bearded dragons show REM and slow wave sleep – brain sleep appeared early in vertebrate evolution
Behavioral sleep is ubiquitous among animals, from insects to man. In humans, sleep is also characterized by brain...
Magnetoreception molecule found in the eyes of dogs and primates
Dog-like carnivores and some primate species may have a magnetic compass similar to that of birds. Cryptochromes are light...
Circuit training: How networks of neurons mediate learning
The brain has an enormous capacity to store information, and to retrieve it again in a highly efficient way that is to...
Faster reconstruction of the connectome
Unraveling the connectivity maps between nerve cells in brains is a huge scientific endeavor – called connectomics. The...
New insight into how the brain processes tastes
Gustation, the sense of taste, is thought to inform the brain about which of the five basic tastes (sweet, sour, salty...
Heavy-metal staining for electron microscopy
The imaging technique to investigate the connectome – the connections between neurons – is electron microscopy (EM)...
Surprising similarity in fly and mouse motion vision
Motion direction is computed by similar types of neural circuits At first glance, the eyes of mammals and those of insects...
Events
Ethics in Science Lecture by Sarah Chan – University of Edinburgh, UK
This year’s Ethics in Science Lecturer will be Dr. Sarah Chan (University of Edinburgh Centre for Biomedicine Self and...
Ethics in Science Lecture by Jean-Pierre Changeux (Honorary President, Neuroscience Department, Institut Pasteur Paris, France)
Time and venue: 17.00 p.m. at the Lecture Hall of the Max Planck Institute for Brain Research, Max-von-Laue-Str. 4, 60438...
Publications
A Molecular Atlas of the Hippocampus: Mapping RNAs and Proteins at Synaptic Resolution
New integrative study uncovers the spatial organization of transcripts and proteins in the mouse hippocampus, offering...
Local translation in neuronal processes
Neurons exhibit a unique degree of spatial compartmentalization and are able to maintain and remodel their proteomes...
Cell-type-specific metabolic labeling, detectionand identification of nascent proteomes in vivo
A big challenge in proteomics is the identification of cell-type-specific proteomes in vivo. This protocol describes how...
Spatially restricted mitochondria fuel the extensive local protein synthesis needed to support synaptic plasticity
Local translation meets protein turnover and plasticity demands at synapses, however, the location of its energy supply is...
Elucidating the control and development of skin patterning in cuttlefish.
Few animals provide a readout that is as objective of their perceptual state as camouflaging cephalopods. Their skin...
Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons
A wealth of data has elucidated the mechanisms by which sensory inputs are encoded in the neocortex, but how these...
Competition for synaptic building blocks shapes synaptic plasticity
Changes in the efficacies of synapses are thought to be the neurobiological basis of learning and memory. The efficacy of...
FluoEM, virtual labeling of axons in 3-dimensional electron microscopy data for long-range connectomics
The labeling and identification of long-range axonal inputs from multiple sources within densely reconstructed EM datasets...
Alternative 3′ UTRs Modify the Localization, Regulatory Potential, Stability, and Plasticity of mRNAs in Neuronal Compartments
Neurons localize mRNAs near synapses where their translation can be regulated by synaptic demand and activity. Differences...
Stabilized supralinear network can give rise to bistable, oscillatory, and persistent activity
A hallmark of cortical circuits is their versatility. They can perform multiple fundamental computations such as...
Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses
In homeostatic scaling at central synapses, the depth and breadth of cellular mechanisms that detect the offset from the...
Spatial Information in a Non-retinotopic Visual Cortex
Turtle dorsal cortex (dCx), a three-layered corticalarea of the reptilian telencephalon, receives inputsfrom the retina...
Training programs
Research That Inspires
Three Weeks of Science, New Perspectives and Discoveries for the Max Planck Junior Scholars 2026 How is scientific...
IMPRS for Neural Circuits
The International Max Planck Research School (IMPRS) for Neural Circuits (Frankfurt am Main, Germany) offers up to ten...





























































































































