Brain Disorders and InjuryDevelopmentResearch News

Brain malformations in the spotlight

Study provides new level of clarity on cerebral cortex development

A study led by Silvia Cappello at the Max Planck Institute of Psychiatry provides the first detailed insights into the extremely complex processes associated with developmental malformations of the human brain. Together with her colleagues, Cappello has developed an integrative multi-level approach that will enable a better understanding of illnesses that develop from brain malformations. This is because although some causes of malformations of the cerebral cortex are known, the exact sequence of events that leads to them is still mostly unclear.


Esther Klingler, Fiona Francis, Denis Jabaudon, Silvia Cappello. (2021). Mapping the molecular and cellular complexity of cortical malformations. Science.  371, 6527, eaba4517.
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